Est. 2014 · Chișinău, MoldovaPeer-Reviewed · Open Access · QuarterlyISSN 2345-1467 · e-ISSN 1857-4696
Peer-reviewed
Open access

Since MMXIV
MJHSMoldovan Journal of Health Sciences
Nicolae Testemițanu
State University of

Medicine & Pharmacy
MJHS
Author

Ala Slobozeanu-Russu

1 articleLatest affiliationMedpark International Hospital, Chisinau, Republic of Moldova

Hypertrophic cardiomyopathy: literature review and case report

Aureliu Batrînac · Ala Slobozeanu-Russu · Natalia Belîi
doi 10.52645/MJHS.2022.1.11pp. 122-133

Introduction

Hypertrophic cardiomyopathy is an autosomal dominant genetic disease. The signs and symptoms of disease vary in terms of history and clinical course, ranging from the development of acute heart failure or even sudden death, while other patients may remain asymptomatic throughout life. At the same time, there is a lack of correlation between the genotype and the phenotype of the disease. Thus, within a family, of two members carrying the same genetic abnormality, one may present a clinical manifestation of severe heart failure, the other remaining asymptomatic.

Clinical case presentation

In this paper, we report a case of a 34-year-old male who comes to see a cardiologist with complaints of moderate-intensity dyspnea, general weakness, and fatigue installed during the post-COVID-19 recovery period.

Management and results

The evolutionary positive dynamics of the disease on the prescribed treatment is followed, as well as the diagnostic criteria for hypertrophic cardiomyopathy.

Discussion

The discussed clinical case of acute cardiac failure in adult otherwise healthy mail is of interest because it rises clinical combinations that were not debated previously: primary diagnosed hypertrophic cardiomyopathy combined with COVID-19, post-COVID-19 isolated myocarditis, hypertrophic cardiomyopathy associated with myocarditis and infection COVID-19. If the suspicion of hypertrophic cardiomyopathy is confirmed, the eventual perianesthetic management of such a patient will change radically. The article presents details of the pathophysiology of hypertrophic cardiomyopathy and key elements for maintaining hemodynamic goals