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Community-acquired pneumonia in chronic heart failure: approach through the oxidative stress and systemic inflammation
Virginia Cascaval1*, Tatiana Dumitras1, Diana Fetco-Mereuta1, Sergiu Matcovschi1, Livi Grib2
https://doi.org/10.52645/MJHS.2025.3.08
Diagnosing community-acquired pneumonia in patients with chronic heart failure can be challenging. Oxidative stress and inflammatory response play an important role in the development and diagnosis of community-acquired pneumonia and are also involved in many cardiovascular diseases, including chronic heart failure.
Targeting the biochemical signature of age-related macular degeneration: a preliminary study of potential diagnostic and prognostic biomarkers
Ecaterina Pavlovschi*, Angela Untila, Svetlana Protopop, Ala Ambros, Olga Tagadiuc
https://doi.org/10.52645/MJHS.2025.3.07
Age-related macular degeneration is a multifactorial, polyetiological condition, affecting individuals over the age of 50, primarily characterized by progressive and irreversible loss of central vision. In the pursuit of a deeper understanding of its etiopathogenesis, risk factors, associated biomarkers, and diagnostic metabolites, the omics approach plays an essential role. The primary objective of this study was to evaluate selected omics biomarkers along with hematological and clinical data and to establish their correlations with macular degeneration.
Hiatal surface area measurement – a useful tool during laparoscopic antireflux surgery
Serghei Cumpătă1*, Vasile Guzun2, Vladimir Iacub1, Evghenii Guțu1
https://doi.org/10.52645/MJHS.2025.3.05
Accurate measurement of the esophageal hiatus is essential during laparoscopic repair of hiatal hernia, especially in patients with gastroesophageal reflux disease. Traditional intraoperative assessments are often subjective and inconsistent. This study proposes a novel, objective method for measuring the hiatal surface area using digital photography and open-source image analysis software.
Diastolic dysfunction and myocardial ischemia in TAVI patients
Marcel Abraș1,2*, Ecaterina Pasat2, Maria-Magdalena Vicol2, Cătălina Ciorici1, Daniela Bursacovschi2
https://doi.org/10.52645/MJHS.2025.3.04
Severe aortic stenosis and ischemic coronary artery disease are frequently associated in elderly patients, adding complexity to interventional management. Diastolic dysfunction, a marker of myocardial impairment and elevated filling pressures, may influence prognosis after transcatheter aortic valve implantation (TAVI), particularly in the presence of concomitant coronary pathology. The aim of the study was to analyze the interaction between severe aortic valve stenosis, left ventricular diastolic dysfunction, and coronary ischemia in elderly patients with complex cardiovascular disease.
Variants of the common carotid artery branching patterns
Nadia Ostahi*, Angela Babuci, Ilia Catereniuc, Anastasia Bendelic, Zinovia Zorina
https://doi.org/10.52645/MJHS.2025.3.03
The common carotid artery is the main source of blood supply to the head and neck regions. Its branching patterns are of great interest in terms of both anatomical and clinical significance. Variability of the common carotid artery can influence the planning of vascular, endovascular and oncological interventions in the head and neck regions, to avoid vessel injuries as well as intra-operative and postoperative complications.
Development of the facial nerve and its specific features
Angela Babuci1*, Zinovia Zorina1, Ilia Catereniuc1, Nataliya Trushel2, Anastasia Bendelic1, Nadia Ostahi1, Sofia Lehtman3
https://doi.org/10.52645/MJHS.2025.3.02
The data reported in the specialty literature on the embryogenesis of the facial nerve mainly refer to the initial stages of its development. Nevertheless, the intrauterine development of the facial nerve is a complex and insightful process, characterized by a range of peculiarities. The goal of our study was to highlight the specific developmental features of the facial nerve for a better understanding of its morphology in adults
The Tirone David procedure in acute type A aortic dissection – when, how, and why? The experience of Professor Dr. George I.M. Georgescu Institute of Cardiovascular Diseases
Grigore Tinică1,2,3, Mihail Enache1,2, Andrei Țărus1,2, Silviu Stoleriu1,2, Alberto Bacușcă1,2
https://doi.org/10.52645/MJHS.2025.3.01
Acute type A aortic dissection represents a life-threatening cardiovascular emergency with catastrophic natural history and extremely high mortality in the absence of prompt surgical intervention. Over the last decades, surgical management has evolved from supracoronary replacement and composite root replacement (Bentall procedure) towards valve-sparing strategies, among which the Tirone David reimplantation procedure has gained increasing acceptance.
Assessment of osteoarticular morbidity in regions with different boron concentrations in deep drinking water of the Republic of Moldova
Maria-Victoria Racu*1, Iurie Pînzaru1, Elena Ciobanu2, Lucia Mazur-Nicorici3
https://doi.org/10.52645/MJHS.2025.2.07
Even if boron is not yet recognized as an essential element for the human body, its insufficient intake is considered harmful, especially for the osteoarticular system. A daily intake of at least 3 mg of boron can fortify bone mass and prevent the onset of osteoarthritis, rheumatoid arthritis, and osteoporosis. This research aims to assess the morbidity caused by rheumatoid arthritis and inflammatory polyarthropathies in the population from regions with different boron concentrations in deep drinking water of the Republic of Moldova.