Stigma surrounding depression continues to be a major barrier to treatment, social inclusion, and recovery. While general attitudes toward mental illness have been widely studied, fewer investigations have focused on the specific beliefs that drive stigma toward individuals with depression in a low- and middle-income country (LMIC) in Eastern European settings, particularly in Moldova.
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Stroke remains a major cause of mortality and disability in Moldova and globally. Rapid prehospital intervention is critical for improving outcomes. The adoption of standardized protocols and checklists has enhanced the efficiency of emergency medical services (EMS), especially in stroke recognition and initial management.
Thiosemicarbazones represent a class of organic compounds with well-documented pharmacological properties, including antitumor, antimicrobial, and antiviral activities. Contemporary research highlights their role in modulating cellular redox equilibrium through antioxidant pathway regulation.
Juvenile idiopathic arthritis is a persistent type of arthritis with no defined cause that develops before the age of 16 years and lasts for at least 6 weeks. The aim of the study was to evaluate cardiovascular risk factors (homocysteine, total cholesterol, and triglycerides) in juvenile idiopathic arthritis.
Osteocalcin, a bone-derived hormone, has emerged as a potential regulator of energy metabolism, with roles in insulin sensitivity, glucose homeostasis, and lipid metabolism. Although an inverse association between osteocalcin and body mass index has been previously reported, data on its link with metabolic parameters in young, otherwise healthy women with obesity remain limited.
Patients with heart failure frequently present with varying degrees of skeletal muscle dysfunction, from early fatigue to sarcopenia and cachexia. Sarcopenia, defined as the loss of muscle mass and/or function, contributes to the physical dimension of frailty. Both conditions are associated with adverse outcomes in heart failure.
The COVID-19 pandemic has posed the biggest challenge to the global health system. Kidney damage is common in COVID-19 and ranges from mild proteinuria to severe acute kidney injury.
Metabolic risk factors for non-communicable chronic diseases develop from an early age, while the clinical manifestations of cardiovascular diseases associated with these risk factors appear later in life. Dyslipidemia is a modifiable risk factor for cardiovascular diseases. The purpose of the study was to evaluate the lipid profile in young people as an early risk factor for cardiovascular disease.
Refractory heart failure with a poor prognosis is a key feature of dilated cardiomyopathy. Inflammatory cardiomyopathy, often diagnosed via in vivo subendomyocardial biopsy, is considered a potential precursor to dilated cardiomyopathy. The Dallas criteria, applied to morphometric and electron microscopic studies of biopsy samples, are essential for differentiating the features of various inflammatory stages. Building upon these established diagnostic principles, our study integrates immunohistological analysis with measurements of intramyocardial indices and intracardiac hemodynamics.
Chronic obstructive pulmonary disease is a major cause of morbidity and mortality worldwide, often associated with multiple comorbidities that may complicate its clinical course. These comorbidities can exacerbate respiratory symptoms, impair lung function, alter imaging findings, and significantly affect prognosis.