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Thrombosis and hemostatic abnormalities in non-Hodgkin lymphoma
Sanda Buruiana1*, Minodora Mazur2
https://doi.org/10.52645/MJHS.2025.2.02
Non-Hodgkin lymphoma is a heterogeneous group of malignant lymphoid tumors. Hemostasis disorders in non-Hodgkin lymphoma are often asymptomatic but can develop into severe complications. The risk of venous thromboembolism increases according to the totality of risk factors assessed directly in each individual patient, based on age, gender, comorbidities, performance status, and both congenital and acquired thrombophilia
Congenital disorders of glycosylation - diagnosis experience in the Republic of Moldova
Daniela Blăniță1*, Chiril Boiciuc1, Alina Nicolescu2, Victoria Sacara3, Natalia Ușurelu1
https://doi.org/10.52645/MJHS.2025.2.01
Congenital disorders of glycosylation (CDG) represent a group of rare diseases with multisystem involvement and exponential expansion, characterized by defects in the glycosylation process, which is essential for the proper functioning of proteins and lipids. These often manifest under the guise of other pathologies. The objective of the study was to diagnose CDG using Isoelectric Focusing of Transferrin (IEFT) in the Republic of Moldova and to identify diseases that mimic CDG.
Tooth extraction with immediate implantation and immediate loading
Immediate loading of dental implants is an evolving discipline requiring validation through clinical and statistical analyses. This study presents a case of immediate implantation and loading to evaluate predictability and outcomes. Immediate restoration reduces treatment time, promotes rapid aesthetic recovery, and addresses patient expectations for functional rehabilitation. Success in such cases relies heavily on maintaining primary stability and avoiding micromovements during osseointegration
Current concepts in the management of calcaneal fractures
Mihaela Sîromeatnicov1
https://doi.org/10.52645/MJHS.2025.1.11
Despite advances in non-operative and surgical management, calcaneal fractures remain severe injuries with relatively poor clinical outcomes. These fractures predominantly affect young, active individuals and are often associated with long-term sequelae, permanent disability, a considerable reduction in quality of life, and a substantial economic impact due to work incapacity and rehabilitation needs.
Artificial intelligence-based techniques for predicting outcomes in COVID-19 patients
Victoria Moghildea1*, Cristina Trofimov2, Ion Grabovschi2, Ruslan Baltaga1, Serghei Sandru1, Sergiu Cobîlețchi1, Oleg Arnaut2
https://doi.org/10.52645/MJHS.2025.1.10
Currently, extensive research has shown that almost all published prediction models are poorly studied and have significant limitations, leading to their predictive performance often being overestimated. Additionally, there is still no universally accepted scoring system, primarily due to the need for adaptation to heterogeneous patient samples (including patient numbers, clinical profiles, and risk factors) and/or ongoing differences in the organization of healthcare systems across various countries.
Gastric intestinal metaplasia and gastric epithelial dysplasia – precursor lesions of gastric cancer
Despite worldwide decreasing trends in the incidence of gastric cancer, the disease remains a significant global health burden, one of the leading causes of cancer death worldwide, and its prevention is a priority for the health system. Intestinal-type gastric carcinoma originates in dysplastic epithelium, which, in turn, develops in the environment of chronic atrophic gastritis and gastric intestinal metaplasia.
The dosage and biological role of carotenoids and chlorophylls in species of the genus Galium L.
Angelica Ohindovschi1,2*, Tatiana Calalb1, Maria Cojocaru-Toma1,2
https://doi.org/10.52645/MJHS.2025.1.08
Carotenoids and chlorophylls are plant pigments that play a vital role in plant life, participating in the process of photosynthesis and in the synthesis of growth regulators, stress signalers and fungicide attack agents. Research from the last decades has shown that, widely used as nutrients, chlorophyll and carotenoid pigments have beneficial effects on the human body. They exert antioxidant, energizing, detoxifying, anti-inflammatory properties, and can be applied in the prevention and treatment of 21st century diseases (cancer, cardiovascular diseases, low immunity), which are related to numerous causal factors (excessive chemicalization of the food industry, progressive climate change and environmental pollution), which reflects on the quality of human health.
Testing and validation of the questionnaire for evaluating the chemical composition of bottled water in relation to public health
Maria Curteanu1,2*, Valentina Marinescu3, Alina Ferdohleb4, Ion Bahnarel1, Iurie Pînzaru1,2, Elena Ciobanu1
https://doi.org/10.52645/MJHS.2025.1.07
In the context of increasing global consumption of bottled water, assessing its chemical composition and impact on public health becomes essential. Although perceived as a safe alternative, bottled water exhibits variability in its chemical composition, and advanced filtration methods can remove essential minerals. Consumers opt for bottled water due to its taste and convenience, yet awareness of associated risks remains limited. This study proposes the development and validation of a questionnaire to evaluate public perceptions of bottled water