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Comparative assessment of active compounds in Solidago species from the flora of the Republic of Moldova
Cornelia Fursenco1,2*, Violeta Alexandra Ion3, Tatiana Calalb1,2, Livia Uncu2,
https://doi.org/10.52645/MJHS.2025.3.20
Solidago virgaurea (European goldenrod) and Solidago canadensis (Canadian goldenrod) are two plant species that have been extensively investigated for their complex phytochemical profiles, particularly represented by flavonoids, phenolic acids, saponins, and essential oils with notable antioxidant and anti-inflammatory properties.
Identifying core stigmatizing beliefs about depression: results from an item-level statistical approach
Jana Chihai1, Andrei Esanu1*, Igor Nastas1,2, Inga Deliv1, Alina Bologan1, Cornelia Adeola1, Radislav Coșulean2, Madalina Bivol2, Mihaela Belous2, Dorin Jelaga1, Romil Popescu1
https://doi.org/10.52645/MJHS.2025.3.18
Stigma surrounding depression continues to be a major barrier to treatment, social inclusion, and recovery. While general attitudes toward mental illness have been widely studied, fewer investigations have focused on the specific beliefs that drive stigma toward individuals with depression in a low- and middle-income country (LMIC) in Eastern European settings, particularly in Moldova.
The effectiveness of using a checklist in prehospital stroke interventions in the Republic of Moldova
Natalia Catanoi1,2, Mihail Peștereanu1*, Larisa Rezneac1,2, Natalia Mocanu1
https://doi.org/10.52645/MJHS.2025.3.17
Stroke remains a major cause of mortality and disability in Moldova and globally. Rapid prehospital intervention is critical for improving outcomes. The adoption of standardized protocols and checklists has enhanced the efficiency of emergency medical services (EMS), especially in stroke recognition and initial management.
Targeting redox balance: antioxidant effects of thiosemicarbazones on human peripheral blood
Valeriana Pantea1, Ecaterina Pavlovschi1,2*, Silvia Stratulat2, Aurelian Gulea3, Olga Tagadiuc2, Valentin Gudumac1
https://doi.org/10.52645/MJHS.2025.3.16
Thiosemicarbazones represent a class of organic compounds with well-documented pharmacological properties, including antitumor, antimicrobial, and antiviral activities. Contemporary research highlights their role in modulating cellular redox equilibrium through antioxidant pathway regulation.
Osteocalcin and metabolic dysfunction in young women with obesity
Carolina Piterschi1,2 ⃰, Lorina Vudu1,2
https://doi.org/10.52645/MJHS.2025.3.14
Osteocalcin, a bone-derived hormone, has emerged as a potential regulator of energy metabolism, with roles in insulin sensitivity, glucose homeostasis, and lipid metabolism. Although an inverse association between osteocalcin and body mass index has been previously reported, data on its link with metabolic parameters in young, otherwise healthy women with obesity remain limited.
Sarcopenia and frailty: risk profiles in patients with chronic heart failure
Anastasia Ivanes1*, Lucia Mazur-Nicorici1, Virginia Șalaru2, Livi Grib1, Snejana Vetrilă1
https://doi.org/10.52645/MJHS.2025.3.13
Patients with heart failure frequently present with varying degrees of skeletal muscle dysfunction, from early fatigue to sarcopenia and cachexia. Sarcopenia, defined as the loss of muscle mass and/or function, contributes to the physical dimension of frailty. Both conditions are associated with adverse outcomes in heart failure.
Lipid profile in young people
Diana Chiosa1*, Rodica Ignat1, Alexei Levițchi2, Ghenadie Curocichin1,2
https://doi.org/10.52645/MJHS.2025.3.11
Metabolic risk factors for non-communicable chronic diseases develop from an early age, while the clinical manifestations of cardiovascular diseases associated with these risk factors appear later in life. Dyslipidemia is a modifiable risk factor for cardiovascular diseases. The purpose of the study was to evaluate the lipid profile in young people as an early risk factor for cardiovascular disease.