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Epidemiological spectrum and diagnostic management of chronic myeloid leukemia – actualization and milestones
Vasile Musteata
Despite the declining overall trend of ASIR, ASDR and age-standardized DALYs at the expense of high SDI quintiles, the CML burden remains stable due to the growing population in developing countries and the aging population in developed countries. Management of patients with primary diagnosed CML, with high risk factors, should include enhanced surveillance for SARS-CoV-2 infection. Diagnostics management of patients with CML includes morphological, cytogenetic and molecular-genetic investigations of the peripheral blood and bone marrow regardless of the phase of clinical evolution, with FISH and RT-PCR as proving resolutive modalities.
Acute autoimmune hemolytic anemia in a patient with systemic lupus erythematosus
Vera Chirca1*, Serghei Popa1, Svetlana Agachi1, Lucia Dutca1, Valeriu Corotaș2
https://doi.org/10.52645/MJHS.2024.3.9
Hematological abnormalities are commonly seen in SLE patients, but hemolytic autoimmune anemia is a rare condition. A timely diagnosis of the cause of hemolytic anemia and proper treatment of lupus by correcting autoimmune disorders are crucial in disease management. Pulse therapy combined with corticosteroids and immunosuppressants is effective in acute relapses of hemolytic anemia.
Management of diabetic retinopathy in pregnancy
The risk of retinopathy development may increase during pregnancy. Serious effects can arise for both the mother and the fetus, even though retinopathy is not common during pregnancy. It is possible to avoid significant retinopathy by carefully planning a young diabetic woman's pregnancy and proceeding promptly to laser photocoagulate in cases of severe non-proliferative retinopathy. A tendency for regress is frequently seen in diabetic retinopathy during the post-natal period. Subsequent pregnancies do not significantly increase the risk of progression if the retinopathy is stable before pregnancy.
Postoperative urinary retention - prevalence and risk factors: prospective, cohort study
Natalia Belîi1,2*, Cătălina Lozan1
https://doi.org/10.52645/MJHS.2024.3.04
The prevalence of postoperative urinary retention in a single-center surgical population from the Republic of Moldova varies between 5.5% and 7.9%, depending on the criteria for postoperative urinary retention applied. This variation highlights the need for a consensus on diagnostic criteria for postoperative urinary retention is needed. Patients with hypertension and diabetes mellitus were more likely to develop postoperative urinary retention. Patients with pre-existing neurological disorders such as positive history for stroke and diabetic polyneuropathy were more susceptible for postoperative urinary retention.
Deep endometriosis – impact on infertility, endometriosis fertility index, and reproductive prognosis (comparative study)
Nadejda Codreanu*, Elena Ivanova
https://doi.org/10.52645/MJHS.2024.3.03
EFI in patients with DIE does not reflect all aspects of infertility and has reservations, and consideration of both physical symptoms and sexual health is crucial in managing DIE to optimize fertility outcomes. These findings open the way to the feasibility of surgical treatment of DIE to improve sexual quality of life, which will reduce the need for IVF and increase the chances of spontaneous pregnancy in patients, but this conclusion requires further investigation in randomized clinical trials.
Childbirth at advanced reproductive age: the impact of biopsychosocial factors on the mode of delivery
Rodica Scutelnic1,2*, Larisa Spinei1
https://doi.org/10.52645/MJHS.2024.3.02
Advanced reproductive age has been associated with a higher risk of cesarean section compared to vaginal delivery. The influence of age is modulated by various sociodemographic, medical, and obstetric characteristics, including area of residence, education level, history of cesarean section, parity, pregnancy and delivery complications, pre-existing chronic conditions, antenatal care and provision of information on risk factors.
Laparoscopic peritoneal lavage – a new treatment strategy in spontaneous bacterial peritonitis and liver cirrhosis
Gheorghe Anghelici1,2, Tatiana Zugrav1,2*, Sergiu Pisarenco1, Oleg Crudu2, Gheorghe Lupu2, Ana Apascaritei1
https://doi.org/10.52645/MJHS.2024.3.01
The laparoscopic approach in spontaneous bacterial peritonitis in patients with decompensated liver cirrhosis allows for better sanitation of the abdominal cavity, improves peritoneal absorption, and deserves establishment as clinical practice for patients with ascites and peritonitis and cirrhosis.