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Importance of urodynamic testing prior to treatment for overactive bladder in women
Mihaela Ivanov1*†, Emil Ceban1†
https://doi.org/10.52645/MJHS.2022.3.04
Overactive bladder (OAB) is a common and chronic complex of symptoms that increases in prevalence with advancing age and has a known adverse effect on the quality of life. OAB is a highly prevalent condition affecting 16.6% people from Europe. Women are more commonly affected, and there is an increased incidence with age. Studies in the United States suggest a prevalence of up to 43% in women. The use of urodynamics in the diagnosis of OAB remains controversial. Although it is a gold standard diagnostic test for detrusor overactivity, it is an invasive procedure and therefore should be limited to those with refractory OAB.
Features of lipid metabolism in membranes of rat cells at experimental traumatic brain injury on the background of chronic alcohol intoxication
Valentin Kresyun1†, Vladlena Godovan1†*, Elena Sokolik1†, Natalya Kresyun1†
https://doi.org/10.52645/MJHS.2022.3.03
Alcohol intoxication is often the cause of traumatic brain injury. The purpose of the work was to study the features of lipid metabolism in erythrocytes and mitochondria of the cerebral cortex cell membranes of rats in traumatic brain injury on the background of chronic alcohol intoxication.
Changes of oxidative stress indices and antioxidant system in the liver tissue on the administration of some coordination compound of copper, derivatives of thiosemicarbazide
Valeriana Pantea1†*, Veaceslav Popa2†, Olga Tagadiuc2†, Lilia Andronache1†, Valentin Gudumac1†
https://doi.org/10.52645/MJHS.2022.3.02
Identification, study and testing of new remedies for treatment approaches of diseases, resulting from imbalance between oxidants and antioxidants in favor of oxidants, with potentially destructive potential and pathogenesis in liver disorders is of particular interest due to the increase in incidence and severity of these pathologies.
Osteomyelitis of the jaws and facial bones caused by drug use (amphetamine, α- pyrrolidinovalerophenone)
Natalia Rusu-Radzichevici
https://doi.org/10.52645/MJHS.2022.4.13
An attempt was made to detect the pathogenetic factors involved in the occurrence of the disease by studying the clinical and laboratory data of 160 patients diagnosed with chronic osteomyelitis of the jaws treated in the clinic of oro-maxillo-facial surgery between 2005 and 2022. The patients studied were or are still drug users who use illicitly produced (amphetamine-type drugs) or other drugs (abbreviated α-PVP).
Pathogenetic correlation of severe sepsis and multiple organ dysfunction syndrome provoked by multiple infections in perinatal period of women
Luminita Mihalcean1*†, Victoria Rotaru2†, Elena Titica2†
https://doi.org/10.52645/MJHS.2022.4.12
Despite significant advances in diagnosis, medical management and antimicrobial therapy, sepsis in the puerperium remains an important cause of maternal morbidity and mortality. The abnormalities associated with the clinical syndrome of sepsis result from a nonspecific innate inflammatory response. This is due to the fact that sepsis represents a systemic inflammatory response syndrome (SIRS) to infection or injury; therefore, it can rapidly progress to septic shock and death despite aggressive treatment.
Osteitis condensans ilii – difficulty in diagnosis and management. Clinical case study
Liliana Groppa1,2†, Marinela Homițchi1†, Valeria Stog1†, Eugeniu Russu1*†, Lia Chișlari1†, Oxana Bujor2,3†, Lilea Taran3†
https://doi.org/10.52645/MJHS.2022.4.11
Osteitis condensans ilii (OCI) is a condition characterized by benign sclerosis of the iliac bone in the portion adjacent to the sacroiliac joints, which is radiologically manifested by triangular opacities at the level of this portion. Among the clinical manifestations, localized low back or lumbosacral pain is often attested, which is found in the gestational or post-partum period. The pain may worsen during physical exertion or during menstruation and may be accompanied by myalgia.
Epidemiological data and diagnosis pitfalls in aggressive extranodal non-Hodgkin’s lymphomas: current issues
Dumitrita Urescu1,2*, Vasile Musteața1,2, Nina Sghibneva-Bobeico1,2, Maria Robu2, Larisa Musteața2, Victor Munteanu1
https://doi.org/10.52645/MJHS.2022.4.10
Non-Hodgkin's lymphoma is a group of malignant tumors that develop from hematopoietic cells located outside the medullary. They are one of the most common forms of hemoblastosis. Non-Hodgkin lymphoma develops in people of all ages. Morbidity of non-Hodgkin lymphoma increases with age reaching its highest level in people over 50 years of age.
Risk management - component part of the quality assurance system of pharmaceutical care
Nicoleta Cheptanari-Birta*†, Stela Adauji†, Mihail Brumărel†
https://doi.org/10.52645/MJHS.2022.4.09
In the pharmaceutical field, the quality management is a priority and the risk management is a valuable component of an effective quality system. It involves anticipating hazards and controlling risk through a process of risk awareness, reduction, and review. The aim of this paper was to reveal the usefulness of modern risk management strategies and to assess the impact of risk management in the provision of quality services by community pharmacies.