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Targeting redox balance: antioxidant effects of thiosemicarbazones on human peripheral blood
Valeriana Pantea1, Ecaterina Pavlovschi1,2*, Silvia Stratulat2, Aurelian Gulea3, Olga Tagadiuc2, Valentin Gudumac1
https://doi.org/10.52645/MJHS.2025.3.16
Thiosemicarbazones represent a class of organic compounds with well-documented pharmacological properties, including antitumor, antimicrobial, and antiviral activities. Contemporary research highlights their role in modulating cellular redox equilibrium through antioxidant pathway regulation.
Changes of oxidative stress indices and antioxidant system in the liver tissue on the administration of some coordination compound of copper, derivatives of thiosemicarbazide
Valeriana Pantea1†*, Veaceslav Popa2†, Olga Tagadiuc2†, Lilia Andronache1†, Valentin Gudumac1†
https://doi.org/10.52645/MJHS.2022.3.02
Identification, study and testing of new remedies for treatment approaches of diseases, resulting from imbalance between oxidants and antioxidants in favor of oxidants, with potentially destructive potential and pathogenesis in liver disorders is of particular interest due to the increase in incidence and severity of these pathologies.