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Thromboprophylaxis in pregnancy, delivery and puerperium: a review of literature and current guidelines
Corina Cardaniuc*, Irina Sagaidac
https://doi.org/10.52645/MJHS.2026.1.13
Venous thromboembolism is one of the leading causes of maternal morbidity and mortality. Pregnancy induces a hypercoagulable state as an adaptive mechanism to prevent hemorrhage during childbirth. These physiological changes significantly increase the risk of venous thromboembolism – by up to six-fold during pregnancy and up to 10-fold during the postpartum period compared to the non-pregnant population. Given these risks, proper identification of patients who may benefit from thromboprophylaxis is essential to improve maternal outcomes.