DiGeorge syndrome, known also as 22q11.2 deletion syndrome, is a rare multisystemic disorder characterized by a wide range of clinical features and may include thymic aplasia and subsequent immunodeficiency, conotruncal cardiac anomalies, typical facial features, palatal abnormalities, and hypocalcemia due to hypoparathyroidism.
Recurrent laryngeal papillomatosis is a rare but significant pediatric condition caused by human papillomavirus types 6 and 11. Characterized by the repeated growth of benign exophytic lesions in the respiratory tract, recurrent laryngeal papillomatosis poses a considerable burden due to its recurrent nature, frequent need for surgical intervention, and potential impact on respiratory function. This study aims to describe the epidemiological profile of pediatric recurrent laryngeal papillomatosis in the Republic of Moldova, identify high-risk groups, and explore the socioeconomic implications of the disease.
COVID-19 is currently considered a systemic disease affecting the immune system, primarily, lungs, heart, central nervous system, kidneys, intestines, liver and spleen. Impaired liver function and the presence of biochemical changes in liver can be found in approximately 14-53% of adults infected with SARS-CoV-2. Impaired liver function in patients infected with COVID-19 may occur due to a direct effect of the virus on hepatocytes, as well as being secondary to factors such as a systemic inflammatory response of the infected host, the onset of hypoxia (associated with lung damage), multiple organ failure, or due to abusive treatment using overlapping and hepatotoxic drugs.
The presence of prolonged sinus pauses is quite rare in children and adolescents with structural normal heart. The decision of the optimal therapeutic tactics is always challenging.
The article highlights the challenge of evaluating visual field disturbances in school-aged children after brain injury due to the lack of reference values. The study aims to determine the utility of visual field evaluation in these children. It contributes new insights by detailing the features of visual field evaluation in children aged 7 to 18 years following brain injury.